Another great loop option involving the Presidio, the Golden Gate Bridge, and the Golden Gate Promenade. Take the Presidio Promenade Path through the Presidio, then return along Crissy Field. Great views and variety.
san francisco Runs
This is a popular place for hill runs and sunset views. It’s about 1 mile to the summit of Twin Peaks, using Twin Peaks Blvd.
Some good running options just south of Great Highway/Ocean Beach. There's a 4.5 mile loop around Lake Merced, some nice trail running in Fort Funston including a 2-mile bike path, and pedestrian paths around the campus of SFSU.
A unique, traffic-free run with views and hills. Angel Island is in the middle of the Bay, accessible by ferry only. There's a 5 mile loop around the island, or a longer run can include the hill to the top. Other trail options too.
Three unbelievable runs. Marin Headlands/GG National Recreation area is challenging & hilly running just over the GG Bridge. Mt. Tam has a switchback fire road to the summit. And Point Reyes has spectacular trails and running options.